2-((4-CHLOROPHENYLAMINO)METHYLENE)MALONIC ACID DIETHYL ESTER - Names and Identifiers
2-((4-CHLOROPHENYLAMINO)METHYLENE)MALONIC ACID DIETHYL ESTER - Physico-chemical Properties
Molecular Formula | C14H16ClNO4
|
Molar Mass | 297.73 |
Density | 1.257±0.06 g/cm3(Predicted) |
Melting Point | 45-46 °C |
Boling Point | 360.2±42.0 °C(Predicted) |
Flash Point | 171.7°C |
Vapor Presure | 2.25E-05mmHg at 25°C |
pKa | -1.42±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.56 |
Use | This product is for scientific research only and shall not be used for other purposes. |
2-((4-CHLOROPHENYLAMINO)METHYLENE)MALONIC ACID DIETHYL ESTER - Introduction
2-((4-Chlorophenylamino)methyl) malonic acid diethyl ester, also known as CMEAA. The following is an introduction to the nature, use, formulation and safety information of CMEAA:
Nature:
-Appearance: Colorless to light yellow oily liquid.
-Solubility: Soluble in organic solvents, such as ethanol, ether, dichloromethane, etc.
-Melting point: About -17 ℃.
-Boiling point: About 365 ℃.
-Density: about 1.167g/cm³.
Use:
CMEAA has a wide range of applications in the chemical field, including but not limited to the following:
-Drug research: It can be used as a drug intermediate for the synthesis of specific types of drugs.
-Surfactant: can be used as a lubricant and emulsifier.
-Catalyst: It can be used as a carrier for catalysts in organic chemical reactions.
Method:
The preparation of CMEAA usually includes the following steps:
1. Diethyl malate and chloroaniline were added to the reaction vessel.
2. The reaction is carried out at an appropriate temperature, and ammonium sulfate or other acidic catalysts are used to promote the reaction.
3. After the reaction, the target product is obtained by distillation and other purification methods.
Safety Information:
- CMEAA has a certain degree of irritation and should avoid contact with skin and eyes.
-During use or storage, keep away from fire and high temperature.
-Wear appropriate protective gloves and glasses when using.
-If inhaled accidentally or ingested by mistake, please seek medical attention promptly.
Last Update:2024-04-09 02:00:44